Understanding how the body’s immune system responds to transplanted cells and genes is critical in developing new therapeutic strategies.

This programme aims to understand the mechanisms of host tolerance to delivered cells and genes.
 

The success of gene therapy relies largely on the availability of gene delivery vectors that confer therapeutic gene expression in target organs with mininal adverse affects on the host. The immunology programme at REMEDI is aimed at addressing the immunological consequences to the host of the use of viral vectors such as Adeno Associated Virus (AAV) vectors and Lentiviral vectors for therapeutic gene delivery.

This work is taking place at NUI Maynooth through an academic partnership with the Institute of Immunology, NUI Maynooth, under the leadership of Dr. Bernard P. Mahon.

Visit http://immunology.nuim.ie for further information.