Fáilte chuig an Institiúid um Leigheas Athghiúnach
Welcome to the Regenerative Medicine Institute (REMEDI®)

Immunology

Assessing Host Immune Response to Stem Cell and Gene Therapy

Understanding how the body’s immune system responds to transplanted cells and genes is critical in developing new therapeutic strategies.

This programme aims to understand the mechanisms of host tolerance to delivered cells and genes.
 

The success of gene therapy relies largely on the availability of gene delivery vectors that confer tehrapeutic gene expression in target organs with mininal adverse affects on the host. The immunology programme at REMEDI is aimed at addressing the immunological consequences to the host of the use of viral vectors such as Adeno Associated Virus (AAV) vectors and Lentiviral vectors for therapeutic gene delivery.

This work is taking place at NUI Maynooth through an academic partnership with the Institute of Immunology, NUI Maynooth, under the leadership of Dr. Bernard P. Mahon.

Visit http://immunology.nuim.ie for further information.

Selected Publications: 

English, K., Barry, F. P. and Mahon, B. P. (2008) Murine mesenchymal stem cells suppress dendritic cell migration, maturation and antigen presentation. Immunol Lett, 115, 50-8.

REMEDI - National Centre for Biomedical Engineering Science, National University of Ireland, Galway - Tel: +353 91 495166 - Email:info@remedi.ie