Fáilte chuig an Institiúid um Leigheas Athghiniúnach
Welcome to the Regenerative Medicine Institute (REMEDI®)

Dr. Siti Ismail

Postdoctoral Researcher
Phone: 
+353 91 493849
Sni102010@gmail.com

Siti's research is investigating the mechanism of mesenchymal stem cells (MSCs) in mediated cardiac repair

Researcher in

Research Project Area: 

This project is an in-vitro study investigating the secretome of the infarcted heart to determine and elucidate the effect of the cardiac microenvironment on MSC phenotype and transcriptional activity for the potential role in the onset of myocardial infarction and repair.

Positions Held: 

2011 - Present   Post-Doctoral Research Associate, REMEDI, NUI, Galway

2010 - 2011   Post-Doctoral Research Associate, Department of Anatomy, Royal College of Surgeons of Ireland (RCSI), Dublin

2009 - 2010   Post-Doctorate Research Associate,  National Institute for Bioprocessing Research and Training (NIBRT), University College Dublin (UCD)

2007 - 2009   Research Associate, Centre of Process Systems Engineering, Department of Chemical Engineering, Imperial College, University of London, London, UK

2005 - 2007   Laboratory Technician, Stem Cells and Regenerative Medicine Centre, Department of Experimental Medicine & Toxicology, Imperial College, London, University of London, London, UK
 

2002 - 2004   Veterinary Officer, Faculty of Veterinary Medicine, Universiti Putra, Malaysia

2001 - 2002   Research Assistant, Neuroendocrine group-Research on the ‘Development of Endocrine Function’, European Neuroscience Institute, Goettingen, Germany

1998 - 1999   Research Assistant, Faculty of Veterinary Medicine, Universiti Putra, Malaysia

Education And Qualifications

2004 - 2009   Ph.D in Stem Cell Bioprocessing, Department of Chemical Engineering & Stem Cells and Regenerative Medicine Centre, Imperial College,  London, UK
 

1998 - 2001   Master of Veterinary Science (MVSc), Faculty of Veterinary Medicine, Universiti Putra, Malaysia

Selected Publications: 

Publications:

1. N. Siti-Ismail, J. M. Polak, A.Mantalaris, 2010. Lung Stem Cell Bioprocessing: Fundamentals of Producing Lung Cells. In: Cell Therapy for Lung Disease. (Book chapter) Imperial College Press. (pg.169-188)

2. Placzek MR, I-Ming C, Hugo MM, Siti-Ismail N, Blanco TM, Lim M, Cha JM, Fauzi L, Kang Y, Yeo DCL, Joan Ma CY, Polak JM, and Mantalaris A, 2009. Stem Cell Bioprocessing: Fundamentals and Principles. Interscience.

3. N. Siti-Ismail, A. E. Bishop, J. M. Polak, A.Mantalaris, 2008. The benefit of human embryonic stem cell encapsulation for prolonged feeder-free maintenance. Biomaterials, 29; 29:3946-3952

4. H. J. Rippon, S.Lane, M. Qin, N.-Siti Ismail, M.R. Wilson, M. Takata, A.E. Bishop, 2008. Embryonic Stem Cells as a Source of Pulmonary Epithelium In Vitro and In Vivo. Proc Am Thorac Soc Vol 5. pp 717–722.

 

Conference Papers

1. N. Siti-Ismail, A. E. Bishop, A.Mantalaris (2009). Engineering lung epithelial cells from embryonic stem cells in 3D rotating bioreactor system. Tissue Engineering Regenerative medicine meeting- North America (TERMIS-NA) 2008. San Diego, 7-10 December 2008.

2. N. Siti-Ismail, A.E. Bishop, A. Mantalaris (2008). Differentiation of murine embryonic stem cells: a 3D culture model of pulmonary epithelial microenvironment. International Society on Stem cell Research Conference (ISSCR) 2008, Philadelphia, USA.

3. N. Siti-Ismail, A.E. Bishop, A. Mantalaris (2008). An integrated 3D bioreactor system to engineer alveolar epithelial cells from murine embryonic stem cells. International Society on Stem cell Research Conference (ISSCR) 2008, Philadelphia, USA.

4. N. Siti-Ismail, A.E. Bishop, A. Mantalaris (2007). A novel protocol for maintaining human embryonic stem cells (hESC) pluripotency in prolonged maintenance culture. The 4th International Meeting of the Stem Cell Network North Rhine-Westphalia, 8-9th October 2007, Dusseldorf, Germany.

5. N. Siti-Ismail, J.M. Polak, A.E. Bishop, A. Mantalaris (2007). Engineering alveolar epithelial cells from murine embryonic stem cells in static and rotating bioreactor. International Society on Stem cell Research Conference (ISSCR) 2007, Cairns, Australia.

6. N. Siti-Ismail, A. Mantalaris, A.E. Bishop (2007). Derivation and differentiation of human and murine embryonic stem cells into alveolar epithelial cells without embryoid body formation. International Society on Stem cell Research Conference (ISSCR) 2007, Cainrs, Australia.

7. N. Siti-Ismail, A.E. Bishop, A. Mantalaris (2006). A novel protocol for maintaining human embryonic stem cells (hESC) pluripotency in prolonged maintenance culture. 25 Years of Embryonic Stem Cells, 18-19 December 2006, Cambridge UK.

8. N. Siti-Ismail, A. Mantalaris, J.M. Polak, A.E. Bishop (2006). Enhanced differentiation of alveolar epithelial cells from human embryonic stem cells (hESC) using conditioned medium. International Society on Stem cell Research Conference (ISSCR) 2006, Toronto, Canada.

9. N. Siti-Ismail, A. Mantalaris, J.M. Polak, A.E. Bishop (2006). A novel protocol for maintaining human embryonic stem cell (hESC) pluripotency during prolonged maintenance culture. International Society on Stem cell Research Conference (ISSCR) 2006, Toronto, Canada.

10. N. Siti-Ismail, A.E. Bishop, A. Mantalaris, L. Yuan-Min, and J.M. Polak (2006). Polymethylpentene (PMP): A Biocompatible polymer for tissue engineering of lung. International Society on Stem cell Research Conference (ISSCR) 2006, Toronto.

11. I Siti-Norhayati, I Rashid, S Ahmad, A Yahya, S M T Sharifah-Suraya, M M Noordin, Y Rosnina, Y Norazlina, S Ramayee (2000). Sheep as a model for heart transplantation - a post mortem study.  5th. Graduate Congress, 1 -2 December 2000, National University Of Singapore, Singapore.
 

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