Eleanor uses gene therapy techniques to promote axon regeneration for spinal cord injury.
Researcher in
When spinal cord injury (SCI) occurs a glial scar is formed resulting in a highly inhibitory environment for the growth of axons, and therefore prevents regeneration within the injury site. This inhibitory environment is mainly due to the presence of chondroitin sulphate proteoglycans (CSPG). My project aims to promote axon regeneration by knocking down CSPG and over expression of a neuronal growth factor, neurotrophin-3. These therapeutics will be delivered by lentivirus.
2006-present
PhD Student
REMEDI (Prof Tim O’Brien)
Gene Therapy for Spinal Cord Injury
2006
Biochemist
Olympus
Diagonists
2004-2006
MSc
REMEDI
Studies on Retroviral Vectors to Controllably Express Genes in Neuronal-Like Cells
Summer 2003
Professional Experience Programme (PEP)
Ludwig-Boltzman institute from tramacology Vienna
Release and hemodynamic influence of nitro-glycerine-derived nitric oxide in endotoxemic rats
2000-2004
BSc Hons in Biotechnology
NUI Galway
Paper;- Release and hemodynamic influence of nitro-glycerine-derived nitric oxide in endotoxemic rats.
Vascular pharmacology
Dec 2005
Poster Presentation
EuroGlia, London
Sept 2007
Poster Presentation:
Irish Society of Gene and Cell Therapy, NUI Galway, Ireland.
May 2007
Poster Presentation:
Irish Society of Gene and Cell Therapy, NUI Cork, Ireland.
May 2008