Senior Technician
Researcher in
Investigation of expression and function of toll-like receptors (TLRs) in dendritic cells from normal and acutely injured kidneys.
Jan 08-present
Senior Technician REMEDI
Immunology related to kidney disease and transplantation
Feb 07- Dec 07
Quality Assurance Sterilisation Engineer
Medtronic Vascular
2005-2007
Technical Operations Scientist
Beckman Coulter
2001-2005
Molecular Biologist
The State Laboratory
Development of quantitative real-time PCR assays to detect genetically modified DNA in food and animal feed
2000-2001
Post-doctoral Researcher
The National Diagnostic Centre
Development of a quantitative real-time PCR assay to detect fungal pathogens in blood.
1995-1999
PhD
University of London Queen Mary and Westfield College Identification and molecular characterisation of a novel pathogenicity island in the human periodontopathogen Porphyromonas gingivalis.
1993-1994
MSc
University of Leicester Development of controlled level of cytokine gene expression from liver cells
2004: IMI Certificate in Supervisory Management
The rag locus of Porphyromonas gingivalis contributes to virulence in a murine model of soft tissue destruction. Infection and Immunity. 75:2071-4. 2007
Evaluation of a PCR/DNA probe colorimetric membrane assay for identification of Campylobacter species in human stool specimens. J. Clinical Microbiology. 39: 4163-4165, 2001
Identificatio of ragAB as a temperature-regulated operon of Porphyromonas gingivalis W50 using differential display of randomly primed RNA. Infection and Immunity.68: 4012-4017. 2000
A 55kDa immunodominant antigen of Porphyromonas gingivalis W50 has arisen via horizontal gene transfer. Infection and Immunity 67:1157-1171. 1999
The rag locus of Porphyromonas gingivalis: a novel pathogenicity island. J. Periodontal Research. 34: 400-405, 1999
I have always had a keen interest in Immunology, particularly in understanding and characterising the molecular basis of bacterial pathogenesis in infectious disease. More recently this interest has grown to include the immunopathology of acute and chronic kidney disease.
My personal interests include hillwalking, cycling, swimming and keeping fit in general.