Linda investigates how microRNAs regulate the differentiation of MSCs.
Linda is also interested in therapeutic potential of adult stem cells, in the nervous , heart and musculoskeletal system
Researcher in
We are interested in how microRNAs regulate the differentiation of Mesenchymal Stem Cells. miRNAs are short non coding RNAs which are important during development and which are known to regulate other kinds of stem cell.
We are also interested in the therapeutic potential of adult stem cells, particularly in the nervous system, heart and musculoskeletal system.
2007-present:
M.Sc. in Regenerative Medicine Course Coordinator
NUI Galway
2005-present:
Senior Stem Cell Investigator
REMEDI
Mechanisms Regulating Mesenchymal Stem Cell Differentiation
2000-2004:
Scientist Osiris Therapeutics, Baltimore, MD, USA
Characterisation and analysis of adult stem cells
1997-2000:
Post-doctoral Research Fellow
Memorial Sloan Kettering Cancer Center, New York, NY, USA Cloning, characterisation and functional analysis of cell surface proteolytic enzymes
1995-1997:
Post-doctoral Research Fellow
Lombardi Cancer Center,
Georgetown University, Washington DC, USA
Investigating the role of proteolytic enzymes in tumour cell invasion and metastasis.
1991-1994:
Ph.D. Student
Medical Research Council Toxicology Unit, Leicester, UK
1987-1991:
Undergraduate Student
Microbiology and Microbial Technology University of Warwick,
Coventry, UK
Neuhuber B, Swanger SA, Howard L, Mackay A, Fischer I. 2008 “Effects of plating density and culture time on bone marrow stromal cell characteristics.” Exp Hematol
Rooney, G.E., Moran, C., McMahon, S.S., Ritter, T., Maenz, M., Flügel, A., Dockery, P., O’ Brien, T., Howard, L., Windebank, A.J., Barry, F.P. (2008) “Gene-Modified Mesenchymal Stem Cells express functionally active Nerve Growth Factor on an engineered poly lactic glycolic acid (PLGA) substrate.” Tissue Engineering.