Cynthia investigates the application of adult human bone marrow derived mesenchymal stem cells to treat osteoarthritis
Researcher in
We are interested in the application of human bone marrow derived mesenchymal stem cells to treat osteoarthritis
2007-present
Senior Scientist
REMEDI, NUI Galway
The application of adult human bone marrow derived mesenchymal stem cells to treat osteoarthritis
2004-2007
Senior Scientist
Johnson & Johnson Regenerative Therapeutics
Providing proof of principle and efficacy data generated in vitro and in vivo data for early stage projects in cartilage repair
2002-2004
Post-Doctoral Fellow
National Institutes of Health, National Institute of Arthritis. Musculoskeletal and Skin Diseases Role of growth factors in regulating chondrocyte extracellular matrix composition
1997-2002
PhD Student
Thomas Jefferson University, Philadelphia, PA
Student of developmental biology and teratology with specific emphasis on the function of growth factors in embryonic limb mesenchymal cell condensation and subsequent differentiation
2008 Contributor to Faculty of 1000 Medicine reviews
2008 Chair of fracture repair scientific sessions at annual ORS meeting
2007 Reviewer of fracture repair abstracts in preparation for annual ORS meeting
2002 & 2003 NIH post-doctoral intramural research training fellowship
2000 Sigma Xi Grant in Aid Research Award recipient
1999 Doctoral student Foerderer fellowship, Thomas Jefferson University
1999 Grand prize of Teratology society student web page design contest. Reviewed in Science vol 287, p1883.
1997 & 1998 Doctoral student Foerderer fellowship, Thomas Jefferson University
A. Flynn, P. Sloane, C. M. Coleman, A. Stocca, L. Mylotte, J. Boucher, G. Shaw, A. Magee, C. McHale, P. Nolan, P. Nash, F. Barry, T. O’Brien. 2008 Elucidation of Engraftment and Efficacy of Syngeneic Mesenchymal Stem Cells in Rodent Myocardial Infarction. Manuscript in preparation.
A. Liew, T. Bowes, J. McDermott, B. Kealy, L. Howard, A. O’Regan, A. Flynn, C.M. Coleman, G. Avalos, F. Barry, T. O’Brien. 2008 Critical role for osteopontin in endothelial progenitor cell (EPC) mediated neovascularisation. Manuscript submitted to Arteriosclerosis, Thrombosis and Vascular Biology.
C.M. Coleman, G.A. Loredo, C.W. Lo and R.S. Tuan. 2003. Correlation of GDF5 and Connexin 43 mRNA Expression During Embryonic Development. Anatomical Record Part A. 275(A): 1117-1121.
C.M. Coleman and R.S. Tuan. 2003. Growth/Differentiation Factor 5 Enhances Chondrocyte Maturation. Developmental Dynamics. 228(2): 208-216.
C. M. Coleman and R.S. Tuan. 2003. Functional Role of Growth/Differentiation Factor 5 in Chondrogenesis of Limb Mesenchymal Cells. Mechanisms of Development. 120(7): 823-836.
L. Shum, C.M. Coleman, Y. Hatakeyama and R.S. Tuan. 2003. Morphogenesis and Dysmorphogenesis of the Appendicular Skeleton. Birth Defects Research (Part C). 69(2): 102-122.
B. Chatterjee, R.A. Meyer, G.A. Loredo, C.M. Coleman, R.S. Tuan and C.W. Lo. 2003. BMP Regulation of the Mouse Connexin-43 Promoter in Osteoblastic Cells and Embryos. Cell Adhesion and Communication. 10(1): 37-50.