Mesenchymal stem cells, Endothelial progenitor cells, Vascular Medicine, Diabetes Mellitus
Researcher in
Aaron is currently involved in the Medtronic/REMEDI Workpackage 5 (Cell Therapy and Angiogenesis for Peripheral Vascular Disease). His current research focuses on the efficacy of Mesenchymal Stem Cells (MSCs) and Ephrin B2 expressing MSCs therapy using a murine model of hindlimb ischaemia. He is also interested in the role of Endothelial Progenitor Cells (EPCs) especially in the diabetic setting and non-viral approaches for efficient MSCs transfection.
July 2010 - Present Postdoctoral Researcher, Regenerative Medicine Institute (REMEDI), NUI, Galway.
2007 - 2010 Specialist Registrar in General Internal Internal Medicine, Our Lady’s Hospital, Navan, Co. Meath
2008 - 2009 Specialist Registrar in Diabetes & Endocrinology/General Internal Medicine, Mater Misericordiae University Hospital, Dublin
2007 - 2008 Specialist Registrar in Diabetes & Endocrinology/General Internal Medicine, Beaumont Hospital, Dublin
2004 - 2007 Specialist Registrar in Diabetes & Endocrinology, University College Hospital Galway
2003 - 2004 Specialist Registrar in Diabetes & Endocrinology/General Internal Medicine, University College Hospital Galway
2000 - 2003 Internship and Senior House Officer Medical Scheme Beaumont Hospital, Dublin
1995 - 2000 Undergraduate Medical Training, Royal College of Surgeons in Ireland (RCSI), Dublin
Educational Qualifications
2004 - 2008 Ph.D in Diabetes & Endocrinology, REMEDI & National University of Ireland, Galway
2002 Membership of the Royal College of Physicians in Ireland (MRCPI)
2000 MB BCh BAO, LRCP&SI, Royal College of Surgeons of Ireland (RCSI), Dublin
2011 Ulysses Grant from Irish Research Council for the Humanities and Social Sciences (IRCHSS), Irish Research Council for Science, Engineering and Technology (IRCSET) & Teagasc
2010 Professor T. J. McKenna Endocrine Research Medal
2010 Novartis Bursary for the Best Abstract (Specialist Registrar in Diabetes & Endocrinology)
2004 Clinical Research Training Fellowship from Health Research Board
2004 Dr. Phil Vizzard Grant from Diabetes Federation Ireland (DFI)
2000 Conjoint First Prize for the Best Undergraduate Oral Presentation (Annual RCSI Research Day)
1999 Dr. FitzPatrick Medal for the Best Pathology Research (Biological Society, RCSI)
1999 Summer Student Research Grant by Royal College of Surgeons in Ireland & Charitable Infirmary Charitable Trust (CICT)
PubMed Link: http://www.ncbi.nlm.nih.gov/pubmed?term=Liew%20Aaron
Bowes T, Hanley SA, Liew A, Eglon M, Mashayekhi K, O'Kennedy R, Barry F, Taylor WR, O'Brien T, Griffin MD, Finlay WJ, Greiser U. Developing Cell-Specific Antibodies to Endothelial Progenitor Cells Using Avian Immune Phage Display Technology. J Biomol Screen. 2011 May 18. [Epub ahead of print] PMID: 21593485
Davenport C, Liew A, Doherty B, Win HH, Misran H, Hanna S, Kealy D, Al-Nooh F, Agha A, Thompson CJ, Lee M, Smith D. The prevalence of adrenal incidentaloma in routine clinical practice. Endocrine. 2011 Mar 10. [Epub ahead of print]
PMID: 21547511Kealy B, Liew A, McMahon JM, Ritter T, O'Doherty A, Hoare M, Greiser U, Vaughan EE, Maenz M, O'Shea C, Barry F, O'Brien T. Comparison of viral and non-viral vectors for gene transfer to human endothelial progenitor cells. Tissue Eng Part C Methods. 2009 Jun;15(2):223-31. PMID: 19196124
Liew A, McDermott JH, Barry F, O'Brien T. Endothelial Progenitor Cells for the treatment of Diabetic Vasculopathy: Panacea or Pandora's Box? Diabetes, Obesity and Metabolism. 2008 May;10(5):353-66. PMID: 17825082
Liew A, Barry F, O'Brien T. Endothelial progenitor cells: diagnostic and therapeutic considerations. BioEssays. 2006 Mar;28(3):261-70. Review. PMID: 16479582
Duffy A, Liew A, O'Sullivan J, Avalos G, Samali A, O'Brien T. Distinct effects of high-glucose conditions on endothelial cells of macrovascular and microvascular origins. Endothelium. 2006 Jan-Feb;13(1):9-16. PMID: 16885062
Murphy M, Mabruk MJ, Lenane P, Liew A, McCann P, Buckley A, O Flatharta C, Hevey D, Billet P, Robertson W, Javed S, Leader M, Kay E, Murphy GM. Comparison of the expression of p53, p21, Bax and the induction of apoptosis between patients with basal cell carcinoma and normal controls in response to ultraviolet irradiation. J Clin Pathol. 2002 Nov;55(11):829-33. PMID: 12401820
Murphy M, Mabruk MJ, Lenane P, Liew A, McCann P, Buckley A, Billet P, Leader M, Kay E, Murphy GM. The expression of p53, p21, Bax and induction of apoptosis in normal volunteers in response to different doses of ultraviolet radiation. Br J Dermatol. 2002 Jul;147(1):110-7. PMID: 12100192
Memberships
Member of the Royal College of Physicians in Ireland (RCPI), Irish Endocrine Society (IES) & European Society of Endocrinology (ESE)
Personal interests:
Fitness & amateur musician
