Dr. Cathal Moran
Research Fellow REMEDI, Specialist Registrar in Orthopaedic Surgery UCHG cathalmoran@rcsi.ie
Linking Cartilage Research to Surgical Intervention
We are investigating the role of mesenchymal stem cell and genetic therapy in cartilage repair following injury. In particular we are interested in the role of inflammation in this process and are looking at ways to modify this to facilitate cartilage repair and prevent or delay progression to osteoarthritis. In addition to the orthobiologic faculty & researchers at REMEDI, including Professor Frank Barry, Dr Mary Murphy and Professor Timothy O Brien, this work involves a collaboration with Professor Christopher Evans at Beth Israel Deaconess Medical Centre, Harvard Medical School, & the surgical faculty at the Cartilage Repair Centre, Brigham & Womens Hospital in Boston. There is a particular focus on translational research in this program.
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July 2010 - present |
Research Fellow, REMEDI & Specialist Registrar in Orthopaedic Surgery, UCHG |
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Cartilage Repair |
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July 2009-June 2010 |
Specialist Registrar in Orthopaedic Surgery, Lecturer, University College Dublin |
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Cartilage Repair |
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July 2006- June 2009 |
Specialist Registrar in Orthopaedic Surgery, Royal College of Surgeons in Ireland & Cappagh National Orthopaedic Hospital |
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Spinal Cord Injury Repair |
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July 2005-
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Orthopaedic Research Fellow, REMEDI |
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Spinal Cord Injury Repair |
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July 2003-June 2005 |
Senior House Officer, RCSI BST Program, Mater Misericordiae University Hospital, Dublin |
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Ductal Carcinoma In Situ of Breast & Meniscofemoral Ligaments of The Knee |
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July 2002- |
Intern, University College Hospital Dublin |
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Molecular Basis For Hereditary Gastric Cancer |
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July 2000- June 2002 |
Research Fellow, Department of Obstetrics & Gynaecology, NUI Galway |
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Molecular & pharmacological analysis of uterine contractilitu & tocolysis |
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July 1999- Sept 1999 |
Research Fellow, Gladstone Institute, University of California, San Francisco |
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Molecular analysis of Apolipoprotein E expression |
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July 1998- June 1999 |
Research Student, Department of Pharmacology, NUI Galway |
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In Vivo ELISA Investigation of Retinoid Administration |
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July 1997-Sept 1997 |
Research Fellow, National Diagnostics Centre, NUI, Galway |
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Molecular analysis in patients with Chronic Fatigue Syndrome |
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2009 |
MD Degree |
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2002 |
MB, BAO, BCh |
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1999 |
BSc in Pharmacology |
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2010 |
The Presidents Medal, Royal College of Surgeons in Ireland |
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2009 |
Cappagh National Orthopaedic Hospital Residents Prize |
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2009 |
National Specialist Registrar Academic Fellowship Program (Health Research Board) |
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2004 |
Annual Meeting of the Association of Surgeons of Great Britain & Ireland Prize Session Winner |
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2002 |
Royal Academy of Medicine in Ireland Surgical Registrars Prize |
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1999 |
Health Research Board (HRB) Science Degree Fellowship for Medical Undergraduates |
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1999 |
UCSF Graduate Student Research Fellowship |
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1998 |
Health Research Board Summer Student Research Grant |
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1998 |
Pharmacia & Upjohn Gold Medal in Pharmacology for Irish Universities |
Translating Science To Surgery: Regeneration of the Orthopaedic Clinician-Scientist
Moran CJ, Shannon FJ, Curtin W, O Byrne J, Barry, F, O Brien T
Journal of Bone & Joint Surgery (Br). Accepted For Publication May 2010. Log 23651
Neurotrophic Factor-Expressing Mesenchymal Stem Cells Survive Transplantation into the Contused Spinal Cord without Differentiating into Neural Cells.
Rooney GE, McMahon SS, Ritter T, Garcia Y, Moran C, Madigan NN, Fluegel A, Dockery P, O'Brien T, Howard L, Windebank AJ, Barry F.
Tissue Eng Part A. 2009 Oct;15(10):3049-59.
Gene-modified mesenchymal stem cells express functionally active nerve growth factor on an engineered poly lactic glycolic acid (PLGA) substrate
Rooney GE, Moran C, McMahon SS, Ritter T, Maenz M, Flügel A, Dockery P, O'Brien T, Howard L, Windebank AJ, Barry FP.
Tissue Eng Part A. 2008 May;14(5):681-90
Analysis of meniscofemoral ligament tension during knee motion.
Moran CJ, Poynton AR, Moran R, O’Brien M.
Arthroscopy. 2006 Apr;22(4):362-6.
Lateral Meniscal Motion Mediated By The Meniscofemoral Ligaments
Poynton A, Moran CJ, Moran R, O’Brien M
Arthroscopy 2010 – Accepted (ARTH-08-509)
Technique of K-wire localisation and removal using ultrasound guidance
Queally JM, Loganathan K, Moran CJ, Harmon D.
Injury Extra. 2008 39, 343-344
Three Tesla MRI for the diagnosis of meniscal and anterior cruciate ligament pathology: a comparison to arthroscopic findings.
Sampson MJ, Jackson MP, Moran CJ, Moran R, Eustace SJ, Shine S.
Clin Radiol. 2008 Oct;63(10):1106-11
Pain Post Ankle Arthrodesis in Patients With Rheumatoid Arthritis
Burke, N, Moran CJ, Quinlan W
The Foot; Accepted March 2010 - YFOOT-D-10-00001R1
Dorgan's Lateral Cross-Wiring of Supracondylar Fractures of the Humerus in Children
Queally J, Walsh J, Moran CJ, Shannon FJ, D’Souza LG
Injury. 2009 Sep 24. [Epub ahead of print]
Role of sentinel lymph node biopsy in high-risk ductal carcinoma in situ patients.
Moran CJ, Kell MR, Flanagan FL, Kennedy M, Gorey TF, Kerin MJ.
Am J Surg. 2007 Aug;194(2):172-5
Laparoscopic mesh repair of a diaphragmatic hernia of Bochdalek.
Joyce M, Moran C, Khan M, Lowe D, McAnena O.
Surg Laparosc Endosc Percutan Tech. 2006 Aug;16(4):267-9.
The role of sentinel lymph node biopsy in ductal carcinoma in situ.
Moran CJ, Kell MR, Kerin MJ.
Eur J Surg Oncol. 2005 Dec;31(10):1105-11
CDH1 associated gastric cancer
Moran CJ, Joyce M, McAnena OJ.
Eur J Surg Oncol. 2005 Apr;31(3):259-64.
Prophylactic Sentinel Lymph Node Biopsy for Ductal Carcinoma in Situ.
Moran CJ, Kell MR, Flanagan F, Kennedy M, Corrigan T, Gorey T, Kerin MJ
British Journal of Surgery. 2004 May; 91 (1): 133
Minimally invasive parathyroidectomy with operative ultrasound localization of the adenoma.
Kell MR, Sweeney KJ, Moran CJ, Flanagan F, Kerin MJ, Gorey TF.
Surg Endosc. 2004 Jul;18(7):1097-8
Expression and Modulation of Rho Kinase in Human Pregnant Myometrium.
Moran CJ, Friel AM, Smith, TJ, Morrison JJ
Molecular Human Reproduction. 2002; 8(2): 196-200
Prenatal detection and perinatal outcome of fetal trisomies 21, 18 and 13 in the absence of routine biochemical or sonographic screening tests.
Moran CJ, Tay JB, Morrison JJ.
Ultrasound Obstetrics and Gynaecology, 2002; 20 (5): 482-5
Duplicated Downstream Enhancers Control Expression of the Human Apolipoprotein E Gene in Macrophages and Adipose Tissue.
Shyh SJ, Allan C, Grehan S, Tse E, Moran C, Taylor JM.
Journal of Biological Chemistry, 2000; 275 (41), 31567-31572
Health Research Board National Specialist Registrar Academic Fellowship Program