Activated pDCs: open to new antigen-presentation possibilities

Nature Immunology 9, 1208 (2008). doi:10.1038/ni1108-1208

Authors: Tineke van den Hoorn
& Jacques Neefjes

Major histocompatibility complex class II molecules present peptides to CD4+ T cells. New findings indicate that conventional and plasmacytoid dendritic cells handle these molecules differently after activation.